Supplementation with flaxseed oil led to significant decreases in sensitivity, transepidermal water loss, skin roughness and scaling. Smoothness and hydration were increased. The ratio of n-6/n-3 dietary fatty acids in plasma decreased.

Upon supplementation with safflower seed oil, only a significant improvement in skin roughness and hydration was observed; however, the effects were less pronounced and determined at a later point in time than with flaxseed oil. The plasma n-6/n-3 fatty acids ratio increased.